背景:Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family.
IL1 is a pleiotropic cytokine.
It is involved in the inflammatory response, cell growth, and tissue repair in the cortex.
The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra).
In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy.
Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma.
IL1B polymorphisms may be involved in susceptibility to SSc.
Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
仕様
サイズ:100ug
種由来:Human
発現宿主:E.coli
純度:>95 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:Please contact us for more information.
アクセッションNo.:NP_000567.1
アミノ酸配列:Ala 117-Ser 269
遺伝子構造:A DNA sequence encoding the mature form of human IL1β (NP_000567.1) (Ala 117-Ser 269) was expressed.
別名(遺伝子名):IL-1;IL-1 beta;IL-1B;IL1-BETA;IL1F2
分子量:17 kDa
組成:Lyophilized from sterile PBS, pH 7.4
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.