背景：X-linked interleukin-1 receptor accessory protein-like 2 （IL1RAPL2） or Interleukin-1 receptor 9 （IL-1R9） is a member of the interleukin 1 receptor family.
This protein is similar to the interleukin 1 accessory proteins.
IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL; which is reportedly involved in nonsyndromic X-linked mental retardation.
IL-1R9/IL1RAPL2 is highly homologous to IL-1R8.
Both forms have no known ligands and receptor are found in the fetal brain.
IL-1R9/IL1RAPL2 may function as a negative receptor.
Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins.
IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci; and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.
仕様
サイズ：1mg
種由来：Human
発現宿主：HEK293 Cells
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_059112.1
アミノ酸配列：Met 1-Glu 356
遺伝子構造：A DNA sequence encoding the extracellular domain （Met 1-Glu 356） of human IL1R9 （NP_059112.1） precursor was expressed with the fused Fc region of human IgG1 at the C-terminus.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
