84-9364-41 Recombinant Human IL-1R8/IL1RAPL1 Protein (aa 1-354, His Tag) 1mg PKSH031795
[Elabscience]特徴
- 背景:Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of interleukin-1 receptor family.
- The protein structurally comprises three extracellular immunoglobulin domains; which presumably mediate binding of an as yet unidentified ligand; a transmembrane region; and an intracellular domain; which is likely to enable signalling via the NFkB pathway.
- The means of signalling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein.
- L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1); a protein widely expressed in neurons and the related chromaffin and PC12 cells.
- IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR).
- It is suggested to affect human cognitive ability to some extent; especially the memory and concentration capability.
仕様
- サイズ:1mg
- 種由来:Human
- 発現宿主:HEK293 Cells
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:NP_055086.1
- アミノ酸配列:Met 1-Leu 354
- 遺伝子構造:A DNA sequence encoding the human IL1R8 (NP_055086.1) extracellular domain (Met 1-Leu 354) was expressed with a C-terminal polyhistidine tag.
- 別名(遺伝子名):IL1R8;IL1RAPL;MRX10;MRX21;MRX34;OPHN4;TIGIRR-2
- 分子量:40 kDa
- 組成:Lyophilized from sterile PBS; pH 7.4
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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84-9364-41
Recombinant Human IL-1R8/IL1RAPL1 Protein (aa 1-354, His Tag) 1mg
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84-9364-40
Recombinant Human IL-1R8/IL1RAPL1 Protein (aa 1-354, His Tag) 100ug
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