背景：The carbonic anhydrases （or carbonate dehydratases） are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues.
The carbonic anhydrasekl （CA） family consists of at least 11 enzymatically active members and a few inactive homologous proteins.
Carbonic anhydrase protein （CA） VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown.
Increased expression of CA-RP VIII was observed in 78％ of colorectal carcinomas.
It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.
仕様
サイズ：1mg
種由来：Human
発現宿主：E.coli
純度：＞94 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：Please contact us for more information.
アクセッションNo.：NP_004047.3
アミノ酸配列：Met 1-Gln 290
遺伝子構造：A DNA sequence encoding the human CA8 （NP_004047.3） （Met 1-Gln 290） was expressed, with a polyhistidine tag at the C-terminus.
組成：Lyophilized from sterile PBS, 15％ glycerol, pH 7.5
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
