背景：Carboxypeptidase A2 （ CPA2 ） is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group.
The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan.
CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide.
Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_001860.2
アミノ酸配列：Met 1-Tyr 417
遺伝子構造：A DNA sequence encoding the pre pro form of human CPA2 （NP_001860.2） （Met 1-Tyr 417） was expressed with a C-terminal polyhistidine tag.
別名（遺伝子名）：Carboxypeptidase A2; CPA2
分子量：46 kDa
組成：Lyophilized from sterile 25mM Tris, 0.15mM NaCl, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
