背景：Carboxypeptidase A1（CPA1）is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains.
CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide.
In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition.
Three different forms of human pancreatic procarboxypeptidase A have been isolated.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞97 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_001859.1
アミノ酸配列：Met 1-Tyr 419
遺伝子構造：A DNA sequence encoding the human CPA1 precursor （NP_001859.1） （Met 1-Tyr 419） was expressed with a C-terminal polyhistidine tag.
別名（遺伝子名）：Carboxypeptidase A1; CPA1; CPA
分子量：47 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
