84-9363-39 Recombinant Human Carbonic Anhydrase XII/CA12 Protein （His Tag）（Active） 1mg PKSH031505
[Elabscience]
特徴
- 背景：Carbonic anhydrases （CAs） are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide.
- CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid.
- CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain.
- It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis.
- Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker.
- rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity.
仕様
- サイズ：1mg
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞97 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：NP_001209.1
- アミノ酸配列：Met 1-Gln 291
- 遺伝子構造：A DNA sequence encoding the extracellular domain of human CA12 （NP_001209.1） （Met 1-Gln 291） was expressed with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：CA12;CAXII;FLJ20151;HsT18816
- 分子量：31.6 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
84-9363-38
Recombinant Human Carbonic Anhydrase XII/CA12 Protein （His Tag）（Active） 50ug
|
|
|
84-9363-39
Recombinant Human Carbonic Anhydrase XII/CA12 Protein （His Tag）（Active） 1mg
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|