背景：The cluster of differentiation （CD） system is commonly used as cell markers in immunophynotyping.
Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell.
There are more than 320 CD unique clusters and subclusters have been identified.
Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell.
Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
Cluster of differentiation 38 （CD38）, also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells （white blood cells）, including CD4+, CD8+, B and natural killer cells.
It shares several characteristics with ADP-ribosyl cyclase 2 CD157.
CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose （cADPR） from NAD+ to ADP-ribose.
It also functions in cell adhesion, signal transduction and calcium signaling.
CD38 has been used as a prognostic marker in leukemia.
It can also be used to identify plasma cells.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞93 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_001766.2
アミノ酸配列：Val 43 – Ile 300
遺伝子構造：A DNA sequence encoding the extracellular domain of human CD38 （NP_001766.2） （Val 43 – Ile 300） was fused with a polyhistidine tag and a flag tag at the N-terminus.
別名（遺伝子名）：ADPRC 1;ADPRC1;T10
分子量：33.2 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
