背景：Stromal derived factors （SDFs） are a loosely defined group of molecules that are generated by stromal cells.
Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family.
Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known.
SDF-2 is first isolated from themousestromal cell lineST2 as asecretory protein.
The amino acid sequence deduced from themurineclone and thehumanhomologare conserved more than 92 ％, and the aa sequence of SDF-2 shows similarity to those ofyeastdolichyl phosphate-D-mannose, protein mannosyltransferases.
SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer.
SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues.
These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.
仕様
サイズ：100ug
種由来：Human
発現宿主：Baculovirus-Insect Cells
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_008854.2
アミノ酸配列：Met 1-Leu 211
遺伝子構造：A DNA sequence encoding the pro form of human SDF2 （NP_008854.2） （Met 1-Leu 211） was expressed with a C-terminal polyhistidine tag.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
