背景：Phospholipase A2, membrane associated, also known as Phosphatidylcholine 2-acylhydrolase 2A, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2 and PLA2G2A, is a peripheral membrane protein which belongs to thephospholipase A2 family.
PLA2G2A is found in many cells and also extracellularly.
The membrane-bound and secreted forms of PLA2G2A are identical.
PLA2G2A has been proposed to play a role in anti-bacterial defense, inflammation and eicosanoid generation, in clearance of apoptotic cells, and in the Wnt signaling pathway.
PLA2G2A is thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis.
PLA2G2A catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
PLA2G2A might be a factor in human colorectal tumorigenesis.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞97 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_000291.1
アミノ酸配列：Met 1-Cys 144
遺伝子構造：A DNA sequence encoding the human PLA2G2A （NP_000291.1） （Met 1-Cys 144） was expressed, with a polyhistidine tag at the C-terminus.
別名（遺伝子名）：MOM1;PLA2;PLA2B;PLA2L;PLA2S;PLAS1;sPLA2
分子量：15.4 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
