背景：The name ＆quot;Pancreasin＆quot; because it is transcribed strongly in the pancreas.
This secreted, tryptic serine protease, also known as Marapsin or PRSS27 （Protease, serine, 27）, which is a member of the peptidase S1 family.
Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin.
Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea.
In fact, marapsin was the second most strongly up-regulated protease in psoriatic lesions, where expression was localized to the upper region of the hyperplastic epidermis.
Similarly, in the hyperproliferative epithelium of regenerating murine skin wounds, marapsin localized to the suprabasal layers, where keratinocytes undergo squamous differentiation.
Marapsin's restricted expression, localization, and cytokine-inducible expression suggest a role in the terminal differentiation of keratinocytes in hyperproliferating squamous epithelia.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：Q9BQR3
アミノ酸配列：Met 1-Lys 290
遺伝子構造：A DNA sequence encoding the human PRSS27 （Q9BQR3） extracellular domain （Met 1-Lys 290） was expressed, fused with a polyhistidine tag at the C-terminus.
別名（遺伝子名）：CAPH2;MPN;UNQ1884/PRO4327
分子量：30.9 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
