背景：Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46 and GAP43, is a cell membrane protein which belongs to theneuromodulin family.
Neuromodulin / GAP43 contains oneIQ domain.
Neuromodulin / GAP43 is associated with nerve growth.
It is a major component of the motile "growth cones" that form the tips of elongating axons.
Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of neurons.
The sudden infant death syndrome （SIDS） is the main cause of postneonatal infant death and its cause is still unknown.
Neuromodulin / GAP43 is a marker of synaptic plasticity and is critical for normal development of the serotonergic innervation.
Neuromodulin / GAP43 is a major cortical cytoskeleton-associated and calmodulin binding protein that is widely and abundantly expressed during development, maintained in selected brain structures in the adult, and reinduced during nerve regeneration.
CAP23 and GAP43 are functionally related intrinsic determinants of anatomical plasticity.
These proteins function by locally promoting subplasmalemmal actin cytoskeleton accumulation.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞96 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：P17677
アミノ酸配列：Met 1-Ala 238
遺伝子構造：A DNA sequence encoding the human GAP43 （P17677） （Met 1-Ala 238） was fused with a polyhistidine tag at the C-terminus.
別名（遺伝子名）：B-50;PP46
分子量：26.2 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
