背景：ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites.
NUDT5 functions as a MutT-related protein and catalyzes the hydrolysis of 8-oxoGDP to 8-oxoGMP, thereby preventing misincorporation of 8-oxoGua into RNA.
NUDT5 may play significant roles in regulating the G1-S transition in mammalian cells.
It can also hydrolyze other nucleotide sugars with low activity.
仕様
サイズ：50ug
種由来：Human
発現宿主：E.coli
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：Please contact us for more information.
アクセッションNo.：Q9UKK9
アミノ酸配列：Glu2-Phe219
遺伝子構造：A DNA sequence encoding the human NUDT5 （Q9UKK9） （Glu2-Phe219） was expressed with a polyhistidine tag at the N-terminus.
別名（遺伝子名）：hYSAH1;YSA1;YSA1H;YSAH1
分子量：26.3 kDa
組成：Lyophilized from sterile 50mM Tris, 10％ glycerol, pH 8.0
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
