背景:PGA4 (Pepsinogen 4; group I); or Pepsinogen A; is a member of the peptidase A1 family.
Pepsin is expressed as a pro-form zymogen; pepsinogen; whose primary structure has an additional 44 amino acids.
Pepsin is stored as pepsinogen so it will only be released when needed; and does not digest the body's own proteins in the stomach's lining.
Five types of zymogens of pepsins; gastric digestive proteinases; are known: pepsinogens A; B; and F; progastricsin; and prochymosin.
There are two major groups of pepsinogen; namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin); and each frequently has isozymogens.
The PGA3; PGA4 and PGA5 genes encode identical human pepsinogen A enzymes.
仕様
サイズ:50ug
種由来:Human
発現宿主:HEK293 Cells
純度:>97 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:P00790
アミノ酸配列:Met 1-Ala 388
遺伝子構造:A DNA sequence encoding the human PGA4 (NP_001073276.1) (Met 1-Ala 388) was fused with a polyhistidine tag at the C-terminus.
別名(遺伝子名):FLJ58952;FLJ77962;PGA3;PGA4;PGA5
分子量:41.7 kDa
組成:Lyophilized from sterile PBS; pH 7.4
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.