背景：CANT1（calcium activated nucleotidase 1） belongs to the apyrase family.
Apyrase is a calcium-activated plasma membrane-bound enzyme （magnesium can also activate it） （EC 3.6.1.5） that catalyses the hydrolysis of ATP to yield AMP and inorganic phosphate.
Two isoenzymes are found in commercial preparations from S.
tuberosum.
One with a higher ratio of substrate selectivity for ATP： ADP and another with no selectivity.
It can also act on ADP and other nucleoside triphosphates and diphosphates with the general reaction being NTP -＆gt; NDP + Pi -＆gt; NMP + 2Pi.
The salivary apyrases of blood-feeding arthropods are nucleotide hydrolysing enzymes are implicated in the inhibition of host platelet aggregation through the hydrolysis of extracellular adenosine diphosphate.
CANT1 functions as a calcium-dependent nucleotidase with a preference for UDP.
Defects in CANT1 are the cause of desbuquois dysplasia.
仕様
サイズ：50ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：Q8WVQ1-1
アミノ酸配列：Gly80-Ile401
遺伝子構造：A DNA sequence encoding the human CANT1 （Q8WVQ1-1） （Gly80-Ile401） was expressed;with the fused Fc region of human IgG1 at the N-terminus.
別名（遺伝子名）：DBQD;SCAN-1;SCAN1;SHAPY
分子量：64.3 kDa
組成：Lyophilized from sterile PBS; pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
