84-9361-94 Recombinant Human SIAE Protein （Baculovirus, His Tag） 50ug PKSH030659
[Elabscience]
特徴
背景：Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds.
It is widely expressed with high expression in the testis, prostate, and colon.
The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase.
Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9（4）-O-acetylesterase, and sialidase.
Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.
Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 （AIS6）.
Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.
仕様
サイズ：50ug
種由来：Human
発現宿主：Baculovirus-Insect Cells
純度：＞97 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：Q9HAT2-1
アミノ酸配列：Met 1-Lys523
遺伝子構造：A DNA sequence encoding the human SIAE （Met 1-Lys523） （Q9HAT2-1） was expressed, with a C-terminal polyhistidine tag.
別名（遺伝子名）：Sialate O-Acetylesterase; H-Lse; Sialic Acid-Specific 9-O-Acetylesterase; SIAE; YSG2;AIS6;CSE-C;CSEC
分子量：57.4 kDa
組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
メーカーマニュアルリンク：メーカーマニュアルはこちら
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