84-9361-86 Recombinant Human RNASET2 Protein （Baculovirus, His Tag） 50ug PKSH030611
[Elabscience]
特徴
背景：RNASET2 （ribonuclease T2） is an enzyme which belongs to the RNase T2 family.
It is highly expressed in the temporal lobe and fetal brain.
RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases.
It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement.
Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly.
An infantile-onset syndrome of cerebral leukoencephalopathy.
Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment, seizures and sensorineural hearing impairment.
The brain shows multifocal white matter lesions, anterior temporal lobe subcortical cysts, pericystic abnormal myelination, ventriculomegaly and intracranial calcifications.
仕様
サイズ：50ug
種由来：Human
発現宿主：Baculovirus-Insect Cells
純度：＞98 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：O00584-1
アミノ酸配列：Met 1-His 256
遺伝子構造：A DNA sequence encoding the human RNASET2 isoform 1 （O00584-1） （Met 1-His 256） was fused with a polyhistidine tag at the C-terminus.
別名（遺伝子名）：Ribonuclease T2;3.1.27.-;Ribonuclease 6;RNASE6PL
分子量：28.5 kDa
組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10％ gly
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
メーカーマニュアルリンク：メーカーマニュアルはこちら
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