背景:ADAMTSL1 is a secreted molecule resembling members of the ADAMTS protein family of matrix metalloproteinases.
Both ADAMTS proteins and ADAM protein family contain a disintegrin and a metalloprotease domain.
Metallospondins is collective term for members of ADAMTS protein family.
ADAMTS proteins lack the EGF-like domain found normally in members of the ADAM protein family.
They also do not possess the canonical disintegrin sequence found in the ADAM protein family.
It contains the domains found in members of the ADAMTS protein family with the exception of the pro-metalloprotease and the disintegrin-like domain typical of this family.
ADAMTSL1 gene is expressed in adult skeletal muscle.
ADAMTSL1 may play an important role in the extracellular matrix as it is deposited in the cell substratum in a punctate fashion and is excluded from focal contacts.
仕様
サイズ:100ug
種由来:Human
発現宿主:Baculovirus-Insect Cells
純度:>97 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:Q8N6G6-2
アミノ酸配列:Met 1-His439
遺伝子構造:A DNA sequence encoding the human ADAMTSL1 (Met 1-His439) (Q8N6G6-2) was expressed, with a C-terminal polyhistidine tag.
別名(遺伝子名):ADAMTSL-1;ADAMTSR1;C9orf94;PUNCTIN
分子量:47 kDa
組成:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.