背景：The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control.
The gene; along with four other related genes; is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications.
The five genes share a remarkably high degree of sequence identity.
Alternative splicing generates additional isoforms of each of the five growth hormones; leading to further diversity and potential for specialization.
This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus.
Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
仕様
サイズ：1mg
種由来：Human
発現宿主：E.coli
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：Please contact us for more information.
アクセッションNo.：P01241
アミノ酸配列：Phe27-Phe217
遺伝子構造：A DNA sequence encoding the human GH1 （P01241） （Phe27-Phe217） was expressed.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
