背景：The protein encoded by this gene is a member of the fibroblast growth factor （FGF） family.
FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells.
Overexpression of this gene has been shown to increase tumor growth and angiogensis.
The adult expression of this gene is restricted to testes and ovaries.
Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor.
Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination.
The alternative splicing of this gene results in four transcript variants.
仕様
サイズ：1mg
種由来：Human
発現宿主：E.coli
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：Please contact us for more information.
アクセッションNo.：NP_149355.1
アミノ酸配列：Gln23-Arg204
遺伝子構造：A DNA sequence encoding the human FGF8a （NP_149355.1） （Gln23-Arg204） was expressed with an initial Met.
別名（遺伝子名）：AIGF;FGF-8;HBGF-8;HH6;KAL6
分子量：21.3 kDa
組成：Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
