背景：The Cluster of Differentiation 31 （CD31） adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 （PECAM-1）, is the only known member of the CAM family on platelets.
CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets.
CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies.
CD31 plays a key role in removing aged neutrophils and tissue regeneration.
CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin ＆alpha;v＆beta;3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
仕様
サイズ：100ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：EAW94208.1
アミノ酸配列：Met 1-Lys 601
遺伝子構造：The mature form of human CD31 （EAW94208.1） extracellular domain （Met1-Lys 601） with five additional amino acids （DDDDK） at the C-terminus was expressed and purified.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
