84-9361-69　Recombinant Human CD9/Tspan-29 Protein （His Tag） 50ug　PKSH030471

特徴

• 背景：The cluster of differentiation （CD） system is commonly used as cell markers in immunophynotyping.
• Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell.
• There are more than 320 CD unique clusters and subclusters have been identified.
• Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell.
• Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
• CD9 is a member of the transmembrane 4 superfamily, which is also known as the tetraspanin family.
• CD9 is a cell surface glycoprotein with 4 hydrophobic domains that is described to complex with integrins and other transmembrane 4 superfamily members.
• It is found expressed on the surface of the exosomes.
• The protein takes part in cellular signal transduction events and thus play a role in the regulation of cell development and activation, growth and motility.
• Besides, CD9 seems to be a key role in the egg-sperm fusion during the mammalian fertilization processes.
• CD9 is found on the membrane of the oocytes and also appears to intervene in maintaining the normal shape of oocyte microvilli.