背景：Platelet-Derived Growth Factor Subunit B （PDGFB） belongs to the PDGF/VEGF growth factor family.
Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin.
PDGFB can exist either as a homodimer （PDGF-BB） or as a heterodimer with the platelet-derived growth factor alpha polypeptide （PDGF-AB）, where the dimers are connected by disulfide bonds.
Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses.
In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
仕様
サイズ：1mg
種由来：Human
発現宿主：Yeast
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：Please contact us for more information.
アクセッションNo.：NP_148937.1
アミノ酸配列：Ser82-Thr190
遺伝子構造：A DNA sequence encoding the human PDGFB （NP_148937.1） （Ser82-Thr190） was expressed with a polyhistidine tag at the N-terminus.
組成：Lyophilized from sterile PBS, 25 ％ Glycerol, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
