84-9360-63 Recombinant Rat Syndecan-1/SDC1 Protein （His Tag） 100ug PDMR100001
[Elabscience]
特徴
- 背景：Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family.
- It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development.
- Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation.
- Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours.
- In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis.
- Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.
仕様
- サイズ：100ug
- 種由来：Rat
- 発現宿主：HEK293 Cells
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P26260
- アミノ酸配列：Met1-Lys253
- 遺伝子構造：A DNA sequence encoding the rat SDC1 （P26260） （Met1-Lys253） was expressed with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：SDC1;Synd1;CD138
- 分子量：25.6 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
84-9360-63
Recombinant Rat Syndecan-1/SDC1 Protein （His Tag） 100ug
|
|
|
84-9360-62
Recombinant Rat Syndecan-1/SDC1 Protein （His Tag） 20ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|