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Recombinant Human SIGLEC2/CD22 Protein （His Tag） 100ug

Elabscience

特徴

  • 背景：Mediates B-cell B-cell interactions.
  • May be involved in the localization of B-cells in lymphoid tissues.
  • Binds sialylated glycoproteins; one of which is CD45.
  • Preferentially binds to alpha-2,6-linked sialic acid.
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface.
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling.
  • Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

シリーズ共通仕様

種由来 Human 発現宿主 HEK293 Cells
純度 ＞95 ％ as determined by reducing SDS-PAGE. エンドトキシン濃度 ＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo. P20273 アミノ酸配列 Asp20-Arg687
遺伝子構造 Recombinant Human CD22 is produced by our Mammalian expression system and the target gene encoding Asp20-Arg687 is expressed with a 6His tag at the C-terminus. 別名（遺伝子名） B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic acid binding Ig-like lectin 2; Siglec-2; SIGLEC2FLJ22814; T-cell surface antigen Leu-14;SIGLEC-2;Siglec-2
分子量 76.2 kDa 組成 Lyophilized from sterile PBS, pH 7.4.
保存条件 Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months. メーカーマニュアルリンク <a href="https://u2.elabscience.com/viewpdf-784564-Elabscience-PDMH100024.pdf" rel="noopener nofollow" target="_blank">メーカーマニュアルはこちら</a>
商品イメージ アズワン品番 商品名 型番 入数 標準価格
（税抜）
定額送料
（税抜）		 備考
Recombinant Human SIGLEC2/CD22 Protein （His Tag） 20ug 84-9357-03 Recombinant Human SIGLEC2/CD22 Protein （His Tag） 20ug PDMH100024 1個 41,000円
Recombinant Human SIGLEC2/CD22 Protein （His Tag） 100ug 84-9357-04 Recombinant Human SIGLEC2/CD22 Protein （His Tag） 100ug PDMH100024 1個 64,000円