特徴
- 背景：CD47（Integrin-AssociatedProtein;IAP）is a 40?60 kDa variably glycosylated atypical member of the immunoglobulin superfamily.
- The ubiquitously expressed CD47 binds to SIRP family members on macrophages; neutrophils; and T cells.
- CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix.
- The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin; and it may play a role in membrane transport and signal transduction.
- This protein has broad tissue distribution; and is reduced in expression on Rh erythrocytes.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：Q08722
- アミノ酸配列：Gln19-Pro139
- 遺伝子構造：Recombinant Human CD47 is produced by our Mammalian expression systemand the target gene encoding Gln19-Pro139 is expressed with a mFc tag at the C-terminus.
- 別名（遺伝子名）：Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; IAP; Protein MER6; CD47; MER6
- 分子量：40.3 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9356-99
Recombinant Human CD47/IAP Protein （mFc Tag） 100ug
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84-9356-98
Recombinant Human CD47/IAP Protein （mFc Tag） 20ug
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