84-9356-92 ［取扱停止］Recombinant Human ICAM-1/CD54 Protein （His Tag） 20ug PDMH100019
[Elabscience]
特徴
- 背景：Inter-Cellular Adhesion Molecule 1 （ICAM1） is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells.
- As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration.
- The presence of heavy glycosylation and other structural characteristics lend ICAM1 binding sites for a number of immune-associated ligands.
- Notably, ICAM-1 binds to macrophage adhesion ligand-1 （Mac-1; ITGB2 / ITGAM）, leukocyte function associated antigen-1 （LFA-1/integrin）, and fibrinogen.ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P05362
- アミノ酸配列：Gln28-Glu480
- 遺伝子構造：Recombinant Human Intercellular Adhesion Molecule 1 is produced by our Mammalian expression system and the target gene encoding Gln28-Glu480 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Intercellular Adhesion Molecule 1; ICAM-1; Major Group Rhinovirus Receptor; CD54; ICAM1
- 分子量：50.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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| 商品イメージ | アズワン品番 商品名 |
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84-9356-92
Recombinant Human ICAM-1/CD54 Protein （His Tag） 20ug
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84-9356-93
Recombinant Human ICAM-1/CD54 Protein （His Tag） 100ug
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