84-9356-70 ［取扱停止］Recombinant Human CDNF/ARMETL1 Protein （His Tag） 20ug PDMH100008
[Elabscience]
特徴
- 背景：erebral Dopamine Neurotrophic Factor （CDNF）, also known as ARMETL1 （ARMET-like protein 1）, is a secreted protein with eight conserved cysteine residues.It is belongs to the ARMET family.
- CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease.
- CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum.
- Human CDNF is glycosylated and secreted from transiently transfected cells.
- CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：Q49AH0
- アミノ酸配列：Gln25-Leu187
- 遺伝子構造：Recombinant Human Conserved Dopamine Neurotrophic Factor is produced by our Mammalian expression system and the target gene encoding Gln25-Leu187 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Cerebral dopamine neurotrophic factor; ARMET-like protein 1; Conserved dopamine neurotrophic factor; ARMETL1
- 分子量：21.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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84-9356-71
Recombinant Human CDNF/ARMETL1 Protein （His Tag） 100ug
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84-9356-70
Recombinant Human CDNF/ARMETL1 Protein （His Tag） 20ug
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