84-9356-63 [取扱停止]Recombinant Human MICB Protein (His Tag)(Active) 100ug PDMH100004
[Elabscience]特徴
- 背景:MHC class I polypeptide-related sequence B; also known as MICB; is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D.
- MICB shares 85% amino acid identity with MICA; a closely related protein; both of which contain three extracellular immunoglobulin-like domains; but without capacity to bind peptide or interact with beta-2-microglobulin.
- acting as a stress-induced self-antigen; binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells; CD8+αβ T cells; and γδ T cells on which the receptor is expressed.
- MICA/B are minimally expressed on normal cells; but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections.
- MICA/B recognition thus is involved in tumor surveillance; viral infections; and autoimmune diseases.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:HEK293 Cells
- 純度:>98 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:Q29980
- アミノ酸配列:Met 1-Gly 298
- 遺伝子構造:A DNA sequence encoding the extracellular domain of human MICB (NP_005922.2) (Met 1-Gly 298) was expressed with a C-terminal polyhistidine tag.
- 別名(遺伝子名):PERB11.2
- 分子量:33 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9356-62
Recombinant Human MICB Protein (His Tag)(Active) 20ug
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84-9356-63
Recombinant Human MICB Protein (His Tag)(Active) 100ug
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