84-9356-60 Recombinant Human NCR2/NKp44/CD336 Protein （His Tag） 20ug PDMH100003
[Elabscience]
特徴
- 背景：Natural cytotoxicity triggering receptor 2 （NCR2）, also known as Natural killer cell p44-related protein （NKp44）, or CD336, is a member of the natural cytotoxicity receptor （NCR） family, which composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain.
- It is a novel transmembrane glycoprotein belonging to the Immunoglobulin superfamily characterized by a single extracellular V-type domain.
- The cytoplasmic domain of NKp44 also contains a sequence that matches the immunoreceptor tyrosine-based inhibitory motif （ITIM） consensus.
- This Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer （NK） cells to mediate tumor cell lysis.
- NKp44 is selectively expressed by IL-2-activated NK cells and may contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis.
- Tumor cell recognition of the mutated NKp44 proteins was significantly reduced and correlated with their lower recognition of heparin.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞88 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：O95944
- アミノ酸配列：Met 1-Pro 190
- 遺伝子構造：A DNA sequence encoding the human NCR2 （NP_004819.2） extracellular domain （Met 1-Pro 190） was fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：CD336;dJ149M18.1;LY95;NK-p44;NKP44;RP1-149M18.2
- 分子量：20 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
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| 商品イメージ | アズワン品番 商品名 |
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84-9356-60
Recombinant Human NCR2/NKp44/CD336 Protein （His Tag） 20ug
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84-9356-61
Recombinant Human NCR2/NKp44/CD336 Protein （His Tag） 100ug
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