84-9356-55 [取扱停止]Recombinant Rhesus macaque B7-H4/VTCN1 Protein (Fc Tag) 100ug PDMC100003
[Elabscience]特徴
- 背景:B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus.
- B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity.
- When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity.
- It also involved in promoting epithelial cell transformation.
仕様
- サイズ:100ug
- 種由来:Rhesus macaque
- 発現宿主:HEK293 Cells
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:F7B770
- アミノ酸配列:Phe29-Ala258
- 遺伝子構造:Recombinant Rhesus macaque B7-H4 is produced by our Mammalian expression system and the target gene encoding Phe29-Ala258 is expressed with a Fc tag at the C-terminus.
- 別名(遺伝子名):B7S1; B7x; Vtcn1; B7h.5; B7-H4; B7H4T-cell costimulatory molecule B7x; B7S1VCTN1; B7XPRO1291; FLJ22418; Immune costimulatory protein B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1
- 分子量:52.5 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
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84-9356-55
Recombinant Rhesus macaque B7-H4/VTCN1 Protein (Fc Tag) 100ug
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84-9356-54
Recombinant Rhesus macaque B7-H4/VTCN1 Protein (Fc Tag) 20ug
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