84-9354-49 ［取扱停止］Recombinant Rat AMPK alpha2 Protein （His Tag） 100ug PDER100002
[Elabscience]
特徴
- 背景：The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase （AMPK）.
- AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits.
- AMPK is an important energy-sensing enzyme that monitors cellular energy status.
- In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase （ACC） and beta-hydroxy beta-methylglutaryl-CoA reductase （HMGCR）, key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol.
- Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
仕様
- サイズ：100ug
- 種由来：Rat
- 発現宿主：E.coli
- 純度：＞85 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションNo.：Q09137-1
- アミノ酸配列：Tyr16-Val195
- 遺伝子構造：A DNA sequence encoding the Rat AMPK alpha2 （Q09137-1） （Tyr16-Val195） was expressed with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：5'-AMP-activated protein kinase catalytic subunit alpha-2;AAPK2;ACACA kinase;Acetyl-CoA carboxylase kinase;AMPK alpha 2 chain;AMPK subunit alpha-2;AMPK2;AMPKa2;AMPKalpha2;HMGCR kinase;Hydroxymethylglutaryl-CoA reductase kinase;PRKAA;PRKAA2;Protein kinase AMP activated alpha 2 catalytic subunit;Protein kinase AMP activated catalytic subunit alpha 2
- 分子量：20 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4., 5％ trehalose, 5％ mannitol, 0.01％ tween-80.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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84-9354-48
Recombinant Rat AMPK alpha2 Protein （His Tag） 20ug
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84-9374-78
Recombinant Rat AMPK alpha2 Protein （His Tag） 20ug
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84-9354-49
Recombinant Rat AMPK alpha2 Protein （His Tag） 100ug
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