特徴
- 背景:Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.
- Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase.
- It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.
- Key regulator of adipocyte differentiation and glucose homeostasis.
- ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.
- Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses.
- Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels.
仕様
- サイズ:20ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>80 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P37231
- アミノ酸配列:Pro234-Tyr505
- 遺伝子構造:A DNA sequence encoding theHuman PPARG protein (P37231) (Pro234-Tyr505) was expressed with a N-His.
- 別名(遺伝子名):PPAR-gamma;Nuclear receptor subfamily 1 group C member 3;PPAR-γ
- 分子量:28 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9345-20
Recombinant Human PPARG protein(His tag) 100ug
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84-9345-19
Recombinant Human PPARG protein(His tag) 20ug
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84-9370-57
Recombinant Human PPARG protein(His tag) 20ug
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84-9370-58
Recombinant Human PPARG protein(His tag) 100ug
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