特徴
- 背景:Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly.Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface.Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility.Binds DNA, with a preference for supercoiled DNA and AT-rich DNA.Does not contribute to the internal structure of mitotic chromosomes.May play a role in chromatin organization.It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P46013
- アミノ酸配列:Lys1001-Pro1112
- 遺伝子構造:A DNA sequence encoding theHuman KI67 protein (P46013) (Lys1001-Pro1112) was expressed with a N-His.
- 別名(遺伝子名):Antigen identified by monoclonal antibody Ki-67;Antigen KI-67;Antigen Ki67
- 分子量:12.4 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9370-55
Recombinant Human KI67 protein(His tag) 20ug
|
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84-9370-56
Recombinant Human KI67 protein(His tag) 100ug
|
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84-9345-18
Recombinant Human KI67 protein(His tag) 100ug
|
|
|
84-9345-17
Recombinant Human KI67 protein(His tag) 20ug
|
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