84-9345-01 ［取扱停止］Recombinant Human MAP1LC3B protein（His tag） 20ug PDEH100091
[Elabscience]
特徴
- 背景：Ubiquitin-like modifier involved in formation of autophagosomal vacuoles （autophagosomes）.Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
- Upon nutrient stress, directly recruits cofactor JMY to the phagophore membrane surfaces and promotes JMY's actin nucleation activity and autophagosome biogenesis during autophagy.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：＞90 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションNo.：Q9GZQ8
- アミノ酸配列：Met1-Gly120
- 遺伝子構造：A DNA sequence encoding theHuman MAP1LC3B protein （Q9GZQ8） （Met1-Gly120） was expressed with a N-His.
- 別名（遺伝子名）：Autophagy-related protein LC3 B;Autophagy-related ubiquitin-like modifier LC3 B;MAP1 light chain 3-like protein 2;MAP1A/MAP1B light chain 3 B;MAP1A/MAP1B LC3 B;Microtubule-associated protein 1 light chain 3 beta
- 分子量：14.1 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
84-9370-40
Recombinant Human MAP1LC3B protein（His tag） 100ug
|
|
|
84-9345-02
Recombinant Human MAP1LC3B protein（His tag） 100ug
|
|
|
84-9345-01
Recombinant Human MAP1LC3B protein（His tag） 20ug
|
|
|
84-9370-39
Recombinant Human MAP1LC3B protein（His tag） 20ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|