84-9344-95 [取扱停止]Recombinant Human CDC42 protein(His tag) 100ug PDEH100088
[Elabscience]特徴
- 背景:Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
- In active state binds to a variety of effector proteins to regulate cellular responses.
- Involved in epithelial cell polarization processes.
- Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase.Regulates cell migration.In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections.Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons.
- In podocytes, facilitates filopodia and podosomes formation upon DOCK11-activation.Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling.Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P60953-2
- アミノ酸配列:Met1-Cys188
- 遺伝子構造:A DNA sequence encoding theHuman CDC42 protein (P60953-2) (Met1-Cys188) was expressed with a N-His.
- 別名(遺伝子名):G25K GTP-binding protein
- 分子量:20.9 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9370-34
Recombinant Human CDC42 protein(His tag) 100ug
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84-9344-95
Recombinant Human CDC42 protein(His tag) 100ug
|
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84-9370-33
Recombinant Human CDC42 protein(His tag) 20ug
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84-9344-94
Recombinant Human CDC42 protein(His tag) 20ug
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