特徴
- 背景:Chemoattractant for blood monocytes, memory T-helper cells and eosinophils.
- Causes the release of histamine from basophils and activates eosinophils.
- May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5.
- One of the major HIV-suppressive factors produced by CD8+ T-cells.
- Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
- The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection.
- The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P13501
- アミノ酸配列:Ser24-Ser91
- 遺伝子構造:A DNA sequence encoding the Human CCL5/RANTES Protein(P13501)(Ser24-Ser91)was expressed with N-SUMO&C-His tag.
- 別名(遺伝子名):C-C motif chemokine 5,EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,T-cell-specific protein RANTES,D17S136E, SCYA5
- 分子量:22.3 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9369-87
Recombinant Human CCL5/RANTES Protein 100ug
|
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84-9344-78
Recombinant Human CCL5/RANTES Protein 20ug
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84-9369-86
Recombinant Human CCL5/RANTES Protein 20ug
|
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84-9344-79
Recombinant Human CCL5/RANTES Protein 100ug
|
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