84-9344-27 [取扱停止]Recombinant Human CXCR4 (C28A) Protein (His Tag) 100ug PDEH100054
[Elabscience]特徴
- 背景:Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation.
- Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels.
- Involved in haematopoiesis and in cardiac ventricular septum formation.
- Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.
- Could be involved in cerebellar development.
- In the CNS, could mediate hippocampal-neuron survival.
- Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates.
- Promotes Env-mediated fusion of the virus.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P61073
- アミノ酸配列:Met1-Lys38
- 遺伝子構造:A DNA sequence encoding the human CXCR4 (C28A) (1M-38K) was expressed with a GST tag at the N-terminus.
- 別名(遺伝子名):C-X-C chemokine receptor type 4, CD184, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, NPYR, SDF 1 receptor, WHIM
- 分子量:31.2kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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84-9344-27
Recombinant Human CXCR4 (C28A) Protein (His Tag) 100ug
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84-9344-26
Recombinant Human CXCR4 (C28A) Protein (His Tag) 20ug
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