84-9344-25　［取扱停止］Recombinant Human Arginase-1 Protein （His Tag） 100ug　PDEH100053

特徴

• 背景：Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme.
• It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver.
• Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung.Arginase is a critical regulator of nitric oxide synthesis and vascular function.
• It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer.
• In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia.
• Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.

仕様

• サイズ：100ug
• 種由来：Human
• 発現宿主：E.coli
• 純度：＞90 ％ as determined by reducing SDS-PAGE.
• エンドトキシン濃度：Please contact us for more information.
• アクセッションNo.：P05089
• アミノ酸配列：Met1-Lys322
• 遺伝子構造：A DNA sequence encoding the human Arginase-1 （1M-322K） was expressed with a polyhistidine tag at the N-terminus.
• 別名（遺伝子名）：ARG1,Al,Arginase 1,Arginase liver,
• 分子量：36.9kDa
• 組成：Supplied as sterile solution of 25mM Tris-HCl+150mM KCl+1mM DTT+20％ glycerol,pH 8.0.
• 保存条件：Store at ＜ -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• メーカーマニュアルリンク：メーカーマニュアルはこちら
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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