84-9344-13 ［取扱停止］Recombinant Human CDK4 Protein （His Tag） 100ug PDEH100047
[Elabscience]
特徴
- 背景：The protein encoded by this gene is a member of the Ser/Thr protein kinase family.
- This protein is highly similar to the gene products of S.
- cerevisiae cdc28 and S.
- pombe cdc2.
- It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression.
- The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16（INK4a）.
- This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product （Rb）.
- Mutations in this gene as well as in its related proteins including D-type cyclins, p16（INK4a） and Rb were all found to be associated with tumorigenesis of a variety of cancers.
- Multiple polyadenylation sites of this gene have been reported.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションNo.：P11802-1
- アミノ酸配列：Ala2-Glu303
- 遺伝子構造：A DNA sequence encoding the Human CDK4 （P11802-1） （Ala2-Glu303） was expressed with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：Cdk 4,cdk4,CDK4 protein,CDK4,Cell division kinase 4,Cell division protein kinase 4,CMM 3,CMM3,Crk3,Cyclin dependent kinase 4,Cyclin-dependent kinase 4,Melanoma cutaneous malignant 3,MGC14458,p34 cdk4,PSK J3,PSK-J3
- 分子量：33.5kDa
- 組成：Lyophilized from sterile PBS, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
84-9344-12
Recombinant Human CDK4 Protein （His Tag） 20ug
|
|
|
84-9344-13
Recombinant Human CDK4 Protein （His Tag） 100ug
|
|
|
84-9369-22
Recombinant Human CDK4 Protein （His Tag） 20ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|