84-9344-05 [取扱停止]Recombinant Human BRCA2 Protein (His Tag) 100ug PDEH100043
[Elabscience]特徴
- 背景:Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer.
- Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair.
- The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair.
- BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P51587-1
- アミノ酸配列:Thr2350-Val2545
- 遺伝子構造:A DNA sequence encoding the Human BRCA2 (P51587-1) (Thr2350-Val2545) was expressed with a polyhistidine tag at the N-terminus.
- 別名(遺伝子名):BRCA 2,BRCA1/BRCA2 containing complex subunit 2,Brca2,BRCA2,DNA repair associated,BRCA2,BRCC 2,BRCC2,Breast and ovarian cancer susceptibility gene early onset,breast and ovarian cancer susceptibility protein 2,Breast cancer 2 early onset,Breast Cancer 2 tumor suppressor,Breast cancer susceptibility protein BRCA2,Breast cancer type 2 susceptibility protein,BROVCA2,FACD,FAD 1,FAD,FAD1,FANCB,FANCD 1,FANCD,FANCD1,FANCD1 gene,Fanconi anemia complementation group D1,Fanconi anemia group D1 protein,GLM3,mutant BRCA2,OTTHUMP00000018803,OTTHUMP00000042401,PNCA2,XRCC11
- 分子量:22.1kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9344-05
Recombinant Human BRCA2 Protein (His Tag) 100ug
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84-9344-04
Recombinant Human BRCA2 Protein (His Tag) 20ug
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84-9369-18
Recombinant Human BRCA2 Protein (His Tag) 20ug
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