84-9343-89 [取扱停止]Recombinant Human Merlin/NF2 protein (His Tag) 20ug PDEH100036
[Elabscience]特徴
- 背景:Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis.
- Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway.
- May act as a membrane stabilizing protein.
- May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.
- Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
仕様
- サイズ:20ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P35240-1
- アミノ酸配列:Met1-Leu595
- 遺伝子構造:A DNA sequence encoding the Human Merlin/NF2 (P35240-1) (1M-595L) was expressed with a polyhistidine tag at the N-terminus.
- 別名(遺伝子名):CAN, BANF, Bilateral acoustic neuroma, MERL_HUMAN, Merlin, Moesin ezrin radixin like protein, Moesin ezrin radizin like, Moesin-ezrin-radixin-like, Neurofibromatosis 2, Neurofibromatosis type 2, Neurofibromatosis2, NF 2, SCH, Schwannomerlin
- 分子量:69.7kDa
- 組成:Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9343-89
Recombinant Human Merlin/NF2 protein (His Tag) 20ug
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84-9343-90
Recombinant Human Merlin/NF2 protein (His Tag) 100ug
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84-9369-11
Recombinant Human Merlin/NF2 protein (His Tag) 20ug
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