84-9343-39 ［取扱停止］Recombinant Human PBEF/NAMPT Protein （His Tag） 20ug PDEH100011
[Elabscience]
特徴
- 背景：Pre-B cell colony enhancing factor （PBEF） was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells; but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase （NAMPT） and the adipokine "visfatin".
- PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion.
- It has intracellular and extracellular forms.
- Most of the intracellular functions of PBEF are due to its role as a Nampt which can induce angiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1.
- Extracellular PBEF has been shown to increase inflammatory cytokines; such as TNF-α; IL-1β; IL-16; and TGF-β1.
- PBEF also increases the production of IL-6; TNF-α; and IL-1β in CD14+ monocyctes; macrophages; and dendritic cells; enhances the effectiveness of T cells.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：＞90 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P43490
- アミノ酸配列：Met1-His491
- 遺伝子構造：Recombinant Human PBEF is produced by our E.coli expression system and the target gene encoding Met1-His491 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Pre-B cell-enhancing factor; Nicotinamide phosphoribosyltransferase; NAmPRTase; Nampt; Pre-B-cell colony-enhancing factor 1; Visfatin; NAMPT; PBEF; PBEF1
- 分子量：57 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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| 商品イメージ | アズワン品番 商品名 |
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84-9343-39
Recombinant Human PBEF/NAMPT Protein （His Tag） 20ug
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84-9343-40
Recombinant Human PBEF/NAMPT Protein （His Tag） 100ug
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