84-9343-35 ［取扱停止］Recombinant Human CDK2 Protein （E.coli, His Tag） 20ug PDEH100009
[Elabscience]
特徴
- 背景：Cyclin-dependent kinase 2 （CDK2） belongs to the cyclin-dependent kinase of Ser/Thr protein kinase.
- CDK2 acts as a catalytic subunit of the cyclin dependent kinase complex, whose activity is restricted to the G1-S phage of the cell cycle, it is essential for the G1/S transition.
- The kinase activity of CDK2 can be regulated by the association with a cyclin subunit, its phosphorylation state and CDK inhibitors.
- The activation of the CDK2/cyclin complex requires the phosphorylation of Thr160 and the dephosphorylation of Try14 and Tyr15.
- The inhibition of CDK2-cyclin complex can also be attributed to association with p27Kip1 and p21Waf1/Cip1.
- The activation of CDK2 has been shown to be necessary for apoptosis of quiescent cells, such as neurons, thymocytes and endothelial cells.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：＞90 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P24941
- アミノ酸配列：Met 1-Leu298
- 遺伝子構造：Recombinant Human Cyclin-Dependent Kinase 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu298 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2
- 分子量：36.1 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4., 5％ trehalose, 5％ mannitol, 0.01％ tween-80.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
84-9343-36
Recombinant Human CDK2 Protein （E.coli, His Tag） 100ug
|
|
|
84-9343-35
Recombinant Human CDK2 Protein （E.coli, His Tag） 20ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|