84-9343-29 ［取扱停止］Recombinant Human IA2/PTPRN Protein （aa 576-950, His Tag） 20ug PDEH100005
[Elabscience]
特徴
- 背景：Receptor-type tyrosine-protein phosphatase-like N （PTPRN） belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily.
- PTPRN contains 1 tyrosine-protein phosphatase domain; is expressed in neuroendocrine cells only.
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation.
- It implicated in neuroendocrine secretory processes.
- It may be involved in processes specific for neurosecretory granules; such as their biogenesis; trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.
- It seems to lack intrinsic enzyme activity; may play a role in the regulation of secretory granules via its interaction with SNTB2.
- This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus （IDDM） patient sera; and thus may be a potential target of autoimmunity in diabetes mellitus.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：Q16849
- アミノ酸配列：Arg576-Gln950
- 遺伝子構造：Recombinant Human Islet Cell Antigen 2/Protein Tyrosine Phosphatase Receptor-type N is produced by our E.coli expression system and the target gene encoding Arg576-Gln950 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTP IA-2; PTPRN; ICA3; ICA512
- 分子量：44.6 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4., 5％ trehalose, 5％ mannitol, 0.01％ tween-80.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9343-29
Recombinant Human IA2/PTPRN Protein （aa 576-950, His Tag） 20ug
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84-9343-30
Recombinant Human IA2/PTPRN Protein （aa 576-950, His Tag） 100ug
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