β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4.
These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures.
β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival.
The BioGems Murine β-NGF Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure β-NGF with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for β-NGF.
It contains NS0-expressed recombinant β-NGF.
The detection antibody is a biotinylated goat polyclonal antibody specific for β-NGF.
The kit is analytically validated with ready to use reagents.