IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages.
Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity.
Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles.
Many of the IL-3 activities depend upon co-stimulation with other cytokines.
The BioGems Murine IL-3 Pre-Coated ELISA （Enzyme-Linked Immunosorbent Assay） kit is a solid phase immunoassay specially designed to measure IL-3 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-3.
It contains E.coli-expressed recombinant IL-3.
The detection antibody is a biotinylated goat polyclonal antibody specific for IL-3.
The kit is analytically validated with ready to use reagents.
