The Trefoil Factor peptides （TFF1, TFF2 and TFF3） are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair.
TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to be expressed in certain cancers, including colorectal, hepatocellular, and in biliary tumors.
TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown.
TFF3 also promotes airway epithelial cell migration and differentiation.
The BioGems Human TFF-3 Pre-Coated ELISA （Enzyme-Linked Immunosorbent Assay） kit is a solid phase immunoassay specially designed to measure TFF-3 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for TFF-3.
It contains E.coli-expressed recombinant TFF-3.
The detection antibody is a biotinylated goat polyclonal antibody specific for TFF-3.
The kit is analytically validated with ready to use reagents.
