TNFRII is a member of the TNFR family of transmembrane proteins, and is expressed in immune cells and certain endothelial cells.
It is a high affinity receptor for TNF-α, but manifests a lower affinity to TNF-β.
Signaling through this receptor regulates various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission.
Soluble TNFRII is capable of inhibiting TNF-α-induced activities by acting as a decoy receptor.
The BioGems Human sTNF Receptor Type II Pre-Coated ELISA （Enzyme-Linked Immunosorbent Assay） kit is a solid phase immunoassay specially designed to measure sTNF Receptor Type II with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for sTNF Receptor Type II.
It contains NS0-expressed recombinant sTNF Receptor Type II.
The detection antibody is a biotinylated goat polyclonal antibody specific for sTNF Receptor Type II.
The kit is analytically validated with ready to use reagents.
