M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts.
It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells.
M-CSF has been shown to play important roles in modulating dermal thickness and fertility.
M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis.
It facilitates hematopoietic recovery after bone marrow transplantation.
The BioGems Human M-CSF Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure M-CSF with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for M-CSF.
It contains E.coli-expressed recombinant M-CSF.
The detection antibody is a biotinylated goat polyclonal antibody specific for M-CSF.
The kit is analytically validated with ready to use reagents.